Heterologous expression of human Neuromedin U receptor 1 and its subsequent solubilization and purification
نویسندگان
چکیده
منابع مشابه
Ovarian regulation of neuromedin U and its local actions in the ovary, mediated through neuromedin U receptor 2.
Neuromedin U (NMU) was originally identified as an anorexigenic peptide that modulates appetite as well as energy homeostasis through the brain-gut axis. Although growing evidence has linked NMU activity with the development of female reproductive organs, no direct expression of and function for NMU in these organs has been pinpointed. Using a superovulated rat model, we found that NMU is direc...
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متن کاملEffects of sex steroid hormones on neuromedin S and neuromedin U2 receptor expression following experimental traumatic brain injury
Objective(s): Neuroprotective effects of female gonadal steroids are mediated through several pathways involving multiple peptides and receptors after traumatic brain injury (TBI). Two of these peptides are including the regulatory peptides neuromedin U (NMU) and neuromedin S (NMS), and their common receptor neuromedin U2 receptor (NMUR2). This study investigates the effects of physiological do...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 2008
ISSN: 0005-2736
DOI: 10.1016/j.bbamem.2008.05.017